Nitish Thakor | The Council for Frontiers of Knowledge

Nitish Thakor

Posted by Mark

Robert Walker


Dept. of Biomedical Engineering
The Johns Hopkins School of Medicine
Baltimore, MD 21205
Tel: 410-955-7093 (Off.), 955-0077 (Lab)
http: //www

Personal: Birth date 2/19/52 Married, four children
U.S. Citizen 12010 Misty Rise Ct. Clarkesville, MD 21029
Tel: 410-531-9037

1969-1974 B.S. Electrical Engineering Indian Institute of Technology, Bombay 1977-1978 M.S. Biomedical EngineeringUniversity of Wisconsin, Madison 1979-1981 Ph.D. Electrical and Computer Eng. University of Wisconsin, Madison


  1. 1974-1976 Electronics Engineer
  2. 1977-1981 Teaching & Research Asst.
  3. Assistant Professor Electrical Eng. & Computer Science
  4. 1984-1986 Assistant Professor Biomedical Engineering
  5. 1987-1994 Associate Professor Biomedical Engineering
  6. 1994- present Professor Biomedical Engineering (Joint appointments in Electrical and Computer Eng.)
  1. 1981-1983 Computers in Biomedical Engineering, Real-time computer systems, Microprocessor Software Design
  2. 1984- present Principles of Design of Biomedical Instrumentation, Advanced Biomedical Instrumentation, Biomedical Sensors, Economic Health Care Technologies,
  3. Neuroengineering Continuing education courses on Microcomputer-based Medical Instrumentation and Biomedical Laboratory Computing, Neuroengineering, Molecular and Cellular Instrumentation 1985- 1990 Director, Master's Degree Program in Biomedical Engineering 1988-present Biomedical Sensors and Instrumentation, Professional Programs in Engineering 2004-present Director, Neuroengineering Training Program.
  1. National Scholarship, India; Graduate Fellowships, University of Wisconsin, Madison2nd Prize, Student Paper Competition, Annu. Conf. Eng. Med. Biol. (1981)
  2. 1st Prize, Paper Competition, Symp. Computer Appl. Med. Care (1982)
  3. Research Career Development Award, The National Institutes of Health (1985-1990)
  4. The Presidential Young Investigator Award, The National Science Foundation (1985-1991)
  5. The Fulbright Fellowship, Cybernetics Institute, Barcelona, Spain, 1987.
  6. Centennial Achievement Medal - University of Wisconsin, School of Engineering, 1993.
  7. Fellow, American Institute of Medical and Biological Engineering, 1996; Fellow, Institute of Electrical and Electronics Engineers (IEEE) 1997, Founding Fellow, Biomedical Engineering Society, 2005.
  8. Distinguished Service Award, Indian Institute of Technology, Bombay, India, 2008 and Distinguished Alumnus Award, Indian Institute of Technology, Bombay, India, 2010.
  9. Technical Achievement Award from IEEE Engineering in Medicine and Biology Society, 2010.
  10. Distinguished Achievement Award, University of Wisconsin, School of Engineering, Madison, WI, 2010.
Basic and applied research on Medical Instrumentation, Micro and Nanotechnology and Signal Processing with focus on Neuroengineering

  1. To sustain an internationally recognized basic research program on basic and clinical neuroscience research on the mechanism and therapy of brain diseases and disorders.
  2. To develop a nationally recognized program for technology development and commercialization of medical instrumentation and technology with a focus on Neuroengineering.
  3. Develop innovative micro and nanotechnologies and prosthetic devices for medical research and clinical applications, especially in the area of neurosciences.
  4. To develop economic medical and health care technology for global health.
  5. To develop innovative technologies and promote their commercialization through University-industry partnerships and spinoffs
  6. To educate students and post-doctoral scientists for careers in academia and industry and to foster a vibrant academic-industry relationship.
  7. To create an innovative educational frame-work through innovative new curricula, emphasis on design in undergraduate curriculum, and to provide professional/continuing training
  8. Publications, presentations, and organizational leadership at national and international conferences and symposia.
  9. To foster research collaboration and education at the international level.
  1. Fellow, IEEE; Fellow; AIMBE; Founding Fellow, Biomed. Eng. Soc.; Sigma Xi
  2. Associate Editor, IEEE Transactions on Biomedical Engineering (1989-2002), IEEE Transactions on Information Technology (1996-2002), J. Ambulatory Monitoring (1988-1994), J. Biological Systems (1992-1996), Annals of Biomedical Engineering (1999-present); Editorial Advisory Board, IEEE T-BME (2002-present); Nanobiotechnology (2005-2008), Biomedical Microdevices and Nanotechnology (2008-present).
  3. Editor-in-Chief, IEEE Transactions on Neural and Rehabilitation Engineering, 2006-present.
  4. Co-Founder and Chief Scientific Officer, Infinite Biomedical Technologies, Baltimore, MD, developer of neurological monitoring technologies for Neuroscience Critical Care and Neurosurgery: raised more than $20 Million from 1997-present.
  5. Co-Founder and Member of the Board, Ikona Medical, CA; developer of endoscopic imaging technology; raised more than $1 Million in funding through SBIR funding
  6. Co-Founder and Member of the Board, Machina Technology, developer of prosthetic limb technologies and Phase I, II awards through SBIR funding from the NIH
  7. Co-Founder and Member of the Board, Vigilant Medical, Baltimore, MD; currently marketing Image and File Share technologies
  8. Reviewer, IEEE Trans. Biomed. Eng., IEEE Trans. Signal Processing, Med. Biol. Eng. Comput., J. Appl. Physiol., J. Electroenceph. Clin. Neurophysiol., J. Cardiac Electrophysiol., Circ. Res., PACE, J. Neurosci. Methods, Brain Res., J. Neurophysiol. IEEE Trans. Biomed. Circuits and Systems, etc.
  9. Member of numerous Special Study Sections and Small Business Grants Study Sections, NIH and NSF; 1985- present; member of several NIH Training Grant study sections
  10. Member, NIH Site Visits; Frequent reviewer for the NSF, Whitaker Foundation and the NIH; 1985-present
  11. Permanent Member (1995-99) Surgery & Bioengineering Study Section, NIH; Review panel, NIDRR, 1998; VA Merit Review (2003); Reviewer Army Research grants (2002-2003; 2004-5); reviewer of several NIH ad hoc panels (2005-2008); Member of Training Grant Review Panel, Panel Chair, Quantum Grants, National Institutes of Health, Frequent reviewer of NIH and NSF grant programs
  12. Referee, Student Paper Competitions: Symposium of Computer Applic. Medical Care, 1984-86, IEEE Int. Conf. Eng. Med. Biol. Soc., 1989-1992
  13. Award Committee: Provost Award, 1998-present; Johns Hopkins University.
  14. Several Professorial promotion ad hoc committees, Johns Hopkins University, including Associate and Full Professor Promotion, Search Committees of Chairs of Radiology, Orthopedic Surgery.
  15. AIMBE Fellows nomination committee, 2003-2005
  16. IEEE Ad Com, 2003-2004; IEEE EMBC Publications Committee; IEEE Ad Com 2006-present (Publications), 2008- (Awards)
  17. Consultant: American Edwards, GST Laboratories, Primary Care Software, Physio Control, Cardiac Pacemakers Inc., Eli Lilly & Co., DVP, Cadent, Infinite Biomedical Technologies..
  18. Advisory Boards: University of Wisconsin-Madison (Biomedical Eng), 2002-2004; University of Washington (Biomedical Engineering), 2005-present; Engineering Research Center, University of Southern California, Engineering Research Center 2004-2009, Cleveland Clinic (Biomedical Engineering): 2005-2008.
  19. Program Reviewer: University of Minnesota, Biomedical Engineering, 2009; University of Pittsburgh, Biomedical Engineering, 2010.
  20. Co-Founder: Infinite Biomedical; Baltimore, MD; Ikona Medical,CA, Machina Technology, Baltimore, MD, Vigilant Medical, Baltimore, MD.
  21. Director, Neuroengineering Training Program, Johns Hopkins University; Member Provost Research Award committee, chair or member of ad hoc promotion committees, member Whiting School of Engineering international program and collaboration group.
  1. Chairman, workshop in "Pacemaker Technology," IEEE Int. Conf. EMBS, 1983;
  2. Tutorial on "Modern techniques of automated ECG analysis," IEEE Int. Conf. EMBS, 1984;
  3. ECG signal processing," IEEE Int. Conf. EMBS, 1985;
  4. "Cardiac arrhythmias, pacing, and defibrillation," and "Medical Instrumentation," Annu. Conf. Eng. Med. Biol. Soc. (ACEMB), 1986; "Evoked potentials," IEEE Int. Conf. EMBS, 1987, 1988;
  5. "Computer applications Track," 1989; "Computers in Cardiology Conference;
  6. "ECG signal processing," IEEE Int. Conf. EMBS, 1990-1991; Track Chair, "Cardiology," IEEE Int. Conf. EMBS, 1991;
  7. Program coordinator, "Neurological Signal Processing," Biomed. Eng. Soc. Annual Mtg., 1991;
  8. Invited chair, "World Congress Biomed. Eng., Kyoto, Japan, 1991;
  9. Int. Track Chair, European Congress Biomed. Eng., 1991;
  10. Co-chair, tutorial program, "Frontiers of Computers in Biomedical Engineering," IEEE Int. Conf. Eng. Med. Biol. Soc., Paris, 1992;
  11. Invited tutorial, "Wavelet analysis of evoked potentials;" Chair, technical sessions on Electrocardiography and Computer Modeling of Arrhythmias; 1992;
  12. Tutorial workshop, "Supercomputers in Biomedical Engineering, " IEEE Int. Conf. EMBS, 1993;
  13. Chair, "Wavelet Analysis," IEEE Int. Conf. EMBS, 1993;
  14. World Congress of Biomedical Engineering, Chair and Tutorials on Supercomputers" and "Computer Applications in Medicine,",
  15. ICASSP Conf, Session Chair, Biomedical Signal Processing, 1995;
  16. Track Chair, Biomedical/Neurological Signal Processing at IEEE Eng. Med. Biol. Soc., Montreal, 1995;
  17. Session Chair, Modeling and Simulation, Computers in Cardiology, 1996;
  18. Tutorial, "Cardiac Bioelectricity." Session chair, "EEG signal processing. Origanizer/teacher: IEEE EMBS Summer School on "Biomedical Signal Processing." Track Chair, Neuroengineering, IEEE EMBS Conf, Hong Kong, 1998, and Atlanta, 1999;
  19. Conference Program Chair, BMES, Seattle, 2000;
  20. Keynote Presentation, Biosignal 2000, Brno, Czech Republic, 2000;
  21. Track Chair, Neural Engineering, BMES Annual Conference, 2001;
  22. Co-Track Chair, IEEE Eng. Medicine Biology Annual Conference, Istanbul, 2001;
  23. Theme Chair, Neural Engineering Systems, IEEE EMBS and BMES Joint Conference, Houston, October, 2002;
  24. Keynote invited speaker, Northeast Bioengineering Conference, April, 2002;
  25. Track Chair, Neuroengineering and Neuromuscular Systems, World Congress, 2003.
  26. Invited Chair, "Biosensors," Third Annual BioMEMS & Biomedical NanoTechnology, 2002, Columbus OH;
  27. Program Committee, Neural Engineering workshop and conference, IEEE Eng. Medicine and Biology Society, Capri, 2003;
  28. Invited Chair, "Biosensors," Fourth Annual BioMEMS & Biomedical NanoTechnology, 2003, Washington DC.
  29. Theme Chair, "Neural Engineering," World Congress of Biomedical Engineering, Sydney, Australia, 2003;
  30. Program Committee, Fourth Annual BioMEMs and Nanotech World 2003 Conference;
  31. Program Co-Chair, 2nd Annual Biodefense Conference, Cambridge Healthtech, Washington D.C., Aug. 2003.
  32. Program Chair, Capital IIT (Pan IIT East Coast Chapter), Fall, 2003.
  33. Theme Chair, "Neural Engineering, Biomedical Engineering Society, Philadelphia, PA, 2004;
  34. Program Committee, Annual BioMEMs and Nanotech World, Aug, 2004 Conference;
  35. Program Co-Chair, 3nd Annual Biodefense Conference, Cambridge Healthtech, Aug, 2004;
  36. Theme Chair, "Brain and Neural Engineering," IEEE Engineering in Medicine and Biology Conference, Shanghai, 2005;
  37. Conference Chair, Satellite Conference, "Micro-Nanotechnology for Neural Interfacing," Beijing, China, 2005;
  38. Theme Chair, Neural Engineering, Biomedical Engineering Society, Baltimore, 2005; Invited Theme Chair, Neuroengineering, MEDI 2005, Hartford, CT.;
  39. Session Chair, ICORR 2007, Netherlands; Invited Theme Chair or session chair for IEEE Engineering Medicine and Biology Conference, 2006-20098;
  40. Chair, Workshop on "Beyond Brain Machine Interface," IEEE Engineering in Medicine and Biology Society Conference, Minneapolis, MN , 2009;
  41. Chair, Frontiers of Biomedical Engineering Track, Biomedical Engineering Society, Pittsburgh, PA, 2009;
  42. Conference Chair, AMA-IEEE Conference on Personalized Medicine, March 21-23, 2010;
  43. Organizing committee: "Grand Challenges in Neuroengineering." IEEE Engineering in Medicine and Biology Society, May 5-7, 2010;
  44. Workshop organizer/Chair, "Beyond Brain Machine Interface; from Motor to Sensory and Cognition," sponsored by Army Research Office, June 20, 2010.
  45. Chair, several technical sessions, IEEE Engineering in Medicine and Biology Conference, Buenos Aeris, August, 2010.
  46. Organizing Committee, 5th International Summer School on Emerging Technologies in Biomedicine, "High Throughput Communication between Brain and Machines," September 26th - October 1st 2010, Patras, Greece.
  1. "Ambulatory Arrhythmia Monitoring," MIT, 1982.
  2. "ECG signal processing for arrhythmia detection," Indian Institute of Technology, Bombay, India, December, 1983.
  3. "Biomedical signal processing," Humboldt Institute, Berlin, August, 1984.
  4. "Design, implementation and evaluation of microcomputer-based ambulatory arrhythmia monitors," Cibernetics Institute, Barcelona, Spain, December, 1986.
  5. "Computer models of Defibrillation," PhysioControl Corp., 1986.
  6. "Biomedical Signal Processing," New Jersey, Institute of Technology, Special Symposium, 1987.
  7. "Computer models of ventricular tachycardia and fibrillation," Cardiac Pacemakers, Inc., Minneapolis, 1988, 1989.
  8. "Ventricular tachyarrhythmia detection," Cardiac Pacemakers, Inc., Minneapolis, 1989.
  9. "Ambulatory monitor for QT-interval analysis in ischemic heart disease," Sympsium on Sudden Death, Barcelona, Spain, March, 1989.
  10. "Computer models of ventricular fibrillation and defibrillation," Eli Lilly, Indianapolis,June, 1991.
  11. "Computer models of fibrillation and defibrillation," Duke University, April, 1991.
  12. "Models of cardiac arrhythmias," Niigata University, Japan, July 1991.
  13. "Evoked potential signal processing," Nihon-Koden, Tokyo, Japan, July, 1991.
  14. "Neurological signal processing for neuro-critical monitoring," Univ. Virginia, February, 1992.
  15. "Shock effects on isolated myocytes studied by the patch clamp method," Purdue Defibrillation conference, September, 1992.
  16. "Detection of cardiac arrhythmias: normal, abnormal, chaotic," Department of Statistics, Ohio State Univerisity, January, 1993.
  17. "Cardiac and neurological signal processing for patient monitoring," Chinese Academy of Sciences, Shanghai, Nanjing, and Beijing, March, 1993.
  18. "Adaptive coherence estimation reveals nonlinear processes due to injury in brain," Special Symp. Biomedical Signal Processing ICASSP Conference, Minneapolis, MN, April, 1993.
  19. "Signal processing and modeling in Cardiology," BMT-Kongress (Joint German, Austrian Swiss Conference on Biomedical Engineering), Graz, Austria, September, 1993.
  20. "Neurocritical Care Monitoring," IEEE Chapter, Carleton University, Ottawa, Canada, October, 1993.
  21. "Modeling and Signal Processing in Cardiology," IEEE Eng. Med. Biol. Soc. Chapter, George Washington University, Washington D.C., November, 1993.
  22. "Supercomputer model for the study of fibrillation," 2nd European Conference on Mathematics as Applied to Biology and Medicine, December, 1993, Lyon, France.
  23. "Wavelet and Time-frequency Methods in Biology and Medicine," Tutorial presented at the World Congress of Biomedical Engineering, Rio de Janneiro, Brazil, August, 1994.
  24. "Frontiers of Computers in Bioimedical Engineering," Tutorial presented at the World Congress of Biomedical Engineering, Rio de Janneiro, Brazil, August, 1994.
  25. "High-speed optical imaging of spiral waves in cardiac tissue," plenary talk (given by student Matthew Fishler) at the Computers in Cardiology Conference, Bethesda, MD, 1994.
  26. "Emerging problems in time-frequency-scale analysis of biomedical signals," Introductory Talk at the Time- frequency and Time-scale Analysis Conference, Philadelphia, October, 1994.
  27. "Fundamental analysis of ventricular fibrillation signals," and "Analysis of transient and time-varying evoked potentials for detection of brain injury," presented at the Bat-sheva Seminar Series, Technion Israel Institute of Technology, Haifa, Israel, March, 1995.
  28. "Signals from the heart and brain: new problems and applications," Biomedical Engineering Conference of Spanish Society in Catalunya, Barcelona, Spain, 1995.
  29. "Advances in Cardiac and Neurological Signal Processing," Shanghai Jiaotong University, Shanghai, P.R. China, November, 1995.
  30. "Biomedical Signal Processing" several lectures presented as a Guest Professor of the Xi'an Jiao Tong University, Xi'an, P. R. China, November, 1995.
  31. "Spiral waves and wavelets in the heart: chaotic cardiac rhythms" invited presentation at the Symposium on Nonlinear Dynamics and Chaos at the CNR, Genoa, Italy, Dec., 1995.
  32. "Advanced biomedical signal processing applications in cardiology, neurology and rehabilitation," University of Pittsuburgh, April, 1996.
  33. "Biomedical applications of signal processing," Northern Illinois University, April, 1996.
  34. "Biomedical signals and instrumentation in cardiology and neurology," Biomedical Engineering Program, University of Pittsburgh, 1996.
  35. "Rotors and spiral waves: models of cardiac arrhythmias," IEEE Annual Int. Conf. Eng. Med. Biol., Symposium on Bioelectricity, Chicago, IL, 1997.
  36. "Spiral Waves and Chaos in Heart," University of Minnesota, 1998
  37. "Sequential hypothesis testing in arrhythmia detection," Medtronic, Inc., 1998.
  38. "Parametric, nonparametric, and dynamical analysis methods for fibrillation detection," CPI/Guidant, 1998.
  39. "Computer models of the heart: from single beat to fatal arrhythmias," Keynote Speaker, IEEE Information Technology Applications in Biomedicine (ITAB '98), Washington D. C., 1998.
  40. "Chaotic Rhythms of the Heart: Models and Signals," IBED '98 Conference, Istanbul, Turkey, May, 1998.
  41. "Chaos in the Cardiac Rhythm", "Neuroengineering," Plenary talks, IV FNCTS (Forum Nacional de Ciencia e Tecnologia em Saude), Curitiba, Brazil, 18-22 Oct, 1998.
  42. "Neuroengineering," Colloquium, Applied Physics Lab, Baltimore, MD, 1999.
  43. "Medical Microsystems," Medical Diagnostic Techniques and Procedures, Indian Institute of Technology, Chennai, India, December, 1999.
  44. "Neuroengineering," and "Medical Microsystems" CIIE, Congreso International de Ingenieria Electronica, Veracruz, Mexico, 2000.
  45. ""Interpreting Brain's Message: Telling Normal from Abnormal." EuroConference, Biosignal 2000, Brno, Czech Republic, June, 2000.
  46. "Entropy and Information Measures of Brain Rhythms," Plenary Talk, IEEE Conference on Statistical Signal Processing, Singapore, 2001.
  47. "S.O.S. from the Brain: Brain's Response to Neurological Injury," Arizona State University, November, 2001.
  48. "Neural Microsystems" Plenary talk, International Biomedical Engineering Conference, Rotorua, New Zealand, Nov 2002.
  49. "Engineer's Contact with the Brain," Keynote presentation, the ICME Conference, Singapore, December 2002.
  50. "Medical Microsystems," Invited presentation, Indian Institute of Technology, Bombay, India, December, 2002.
  51. "Time Dependent Entropy and Information Measures of Brain Injury," Neuronal Variability and Noise, Dynamical Neurosciences Symposium, Society for Neuroscience, November, 2003.
  52. "Clinical Neuroengineering: Brain Monitoring from Bench to Bedside," University of Akron, OH, 2003
  53. "Integrated Neurochemical Sensing: Interfacing VLSI to micro/nanosensors" Bringham Young University, 2003.
  54. "Brain signals as information carrier of brain-computer interface: beyond electrical," BIOSIGNAL 2004, Brno, Czech Republic, June 2004.
  55. "Nanobioengineering," 2nd Summer School on Emerging Technologies in Biomedicine, Patras, Greece, 20¬25 June, 2004.
  56. "Nanotechnology: Frontiers of Biomedical Engineering," Indian Institute of Technology, Roorkee; Indian Institute of Technology, Kanpur, 2005.
  57. "Frontiers of Neuroengineering," Satellite Symposium, IEEE Eng Med Biol Soc, Beijing, 2005.
  58. "Clinical Neuroengineering," Invited keynote talk; Biomedical Engineering Society, 2005.
  59. "Neuroengineering: from Bench to Bedside," MEDI 2005, Hartford, CT, 2005.
  60. "A Bench to Bedside Story or How to Bring Ideas from Lab to Clinic?" Albert Eienstein, Neurology Grand Rounds; "
  61. "A Bench to Bedside Story or How to Bring Ideas from Lab to Clinic?" Department of Biomedical Engineering, Drexel University, January, 2006.
  62. "Interfaces to Brain and Mind," University of California, Department of Biomedical Engineering, Irvine, January 2006.
  63. Distinguished Speaker Seminar "Neural Control of Prosthesis: Circuits, Signals and Systems," Michigan State University, April 2006.
  64. "Neuroengineering Symposium" University of Minnesota, Medical Instrumentation Design Conference, Minneapolis, April, 2006.
  65. Invited keynote Speaker, "Neuroengineering" BIO-Korea, Sep 6-8, Seoul, Korea, 2006.
  66. "Signals and Systems for Neural Control of Dexterous Hand Prosthesis," Neural Interface Workshop, Joint China-USA (National Science Foundation), Kunming, China, July 9-11, 2006.
  67. "Brain Machine Interface and Neural Prosthesis," National Science Foundation, Collaborative Research in Computational Neurosciences, University of Marlyand, College Park, June 2006.
  68. "Towards Dexterous Hand Prosthesis: Manipulation with Brain-Machine Interface," University of Virginia, Charlottesville, VA, 26 October, 2007.
  69. "Body or Brain? Control of Dexterous Prosthesis" University of Delaware, Neward, Delaware, November 16, 2007.
  70. "Neural Signal Processing for Brain Machine Interface/Neural Prosthesis," IMIT and University of Melbourne, Melbourne, December, 2007.
  71. Conference Plenary Speaker, IEEE Circuits and Systems and Signal Processing Society, "Circuits, Signals and Systems for Brain Machine Interface and Neural Prosthesis", March, 2008.
  72. "Neural Prosthesis and Deep Brain Stimulation," American Institute of Medical and Biomedical Engineering- AIMBE- Military Collaboration: Bioengineering Challenges of Brain Trauma, Washington DC, February 20, 2008.
  73. "Brain Computer Interface: Theory and Applications," 6nd Summer School on Emerging Technologies in Biomedicine, Patras, Greece, July 3-5, 2008.
  74. "The Brain-Machine Interface and Neural Implants," 16th Annual World Congress on Anti-Aging, July 17, 2008.
  75. "Neural Interfaces for Monitoring and Control," 8th IEEE International Conference on BioInformatics and BioEngineering (BIBE 2008), October 8-10, 2008.
  76. "Mind Over Matter: Building a Brain Machine Interface," Department of Neurology, Johns Hopkins School of Medicine, September 29, 2008.
  77. National Semiconductor Distinguished Faculty Seminar, "Medical Microelectronics: form Circuits, to Systems to Applications," June 15, 2009.
  78. "Clinical Neuroengineering: Monitoring the Brain from Bench to Bedside," Workshop on Engineering the Future of Medicine via Innovation and Collaboration, Postech, Korea, June 17-18, 2009.
  79. Plenary Talk "Taking Neural Signal Processing from Bench to Bedside," The 6th International Workshop on Biosignal Interpretation." Yale University, June 23-26, 2009.
  80. "Connecting Brain to Hand: Circuits and Signals for Neuroprosthetics," Keynote Speaker, BioCAS conference, Beijing, China, Nov 25-27, 2009.
  81. "Neuroengineering," Shanghai Jiao Tong University, Dec 3, 2009.
  82. "Decoding and Dexterity in Neuroprosthesis - Journey into Dimensionality," Invited Speaker, Beijing BCI 2009 Symposium, Tsinghua University Conference on Neuroengineering, Dec 5-6, 2009. • Keynote Speaker, "From Myoprosthesis to Neuroprosthesis," ISSNIP Biosignals and Biorobotics Conference 2010, Vittoria, Brazil, January 4-6, 2010. • "From Myprosthesis to Neuroprosthesis: Emerging Technologies in Human-Machine Inteerface," ISSNIP, Vittoria, Brazil, January 2010. • "Neuroprosthesis: from Monkey to Man", Louisiana Tech University, March 15, 2010 • Decade of Mind VI Conference: "Cognitive Science and Neurotechnologies: Looking Forward to the Next Ten Years". Singapore, October 18-20, 2010. • "Decoding and Dexterity in Neuroprosthesis - Journey into Dimensionality" University of California, Berkeley. • Brain Machine Interface for Control of Prosthesis: What Does it Teach about how Brain in Organized and Codes Information?" Society for Experimental Biology, April 28, 2010. • "Decoding and Augmenting Brain Machine Interface," BIOISION, Alexandria, Egypt, April 14, 2010. • "Neural Interfaces", Distinguished Lecturer, IEEE Circuits Society, Postech University, Korea, May 14, 2010. • "Mind-Brain-Machine Interface with Neural Microsystems," A-STAR, Singapore, October, 2010. • "Revolutionizing Prosthetics with Mind-Brain-Machine Interface," 6th Decade of the Mind Conference, Singapore, October, 2010. • "Revolutionizing Prosthetics: A Brain Machine Interface Solution," University of Wisconsin, October, 2010. • "Neuroengineering: Cells, Chips, Brains and Machines," invited presentation at Krasow Institute, George Mason University, VA, March 2011. • "Revolutionizing Prosthesis with BMI," Plenary Presentation, First Middle East Conference on Biomedical Engineering, Sharjah, UAE, February, 2011. • "Signals and Networks - from Neurons to Brain, for Building Brain Machine Interface," invited presentation, Carnegie Mellon University, March 21, 2011. • "Implanting the Brain Machine Interface: Circuits, Signals and Systems" Keynote Speaker, IEEE NEWCAS, Bordeaux, France, June, 2011. • " Cortical Signals and Decoding Strategies for Dexterous Prosthesis," Invited presentation, 3rd Annual Workshop on Brain-Machine Interfaces, IEEE Systems, Man, Cybernetics, Anchorage, Alaska, October, 2011. • "High Dimensional BMI," Keynote Speaker, IEEE BIOCAS, San Diego, Nov, 2011.

  1. Title: Neuroengineering Training Grant (1T32EB005176) Agency: National Institutes of Biomedical Imaging and Bioengineering (NIBIB) (PI: Thakor) Total: $1,646,251 (directs); $1,767,713 (direct and indirect); Duration: 5/1/10-4/30/1309 This is a predoctoral training grant for up to 10 candidates in the field of Neuroengineering. The program supports education and research in the field of Neuroengineering (subcomponents; Instrumentation, Signals, Imaging, Modeling, Systems Physiology). Title: The REPAIR program (contract: 19GM-1088724) Agency: DARPA, co-investigator with Richard Andersen, Cal Tech; Marc Schieber, University of Rochester, Gerald Loeb, University of Rochester Total: $ 700,000 (direct, Phase 1) Duration: 4/1/2010-3/31/2012 This is a collaborative project involving four research groups to study the cortical mechanism of brain connectivity in formulating motor tasks and motor system, and using experimental and computational model to mimic and study the effects of injury or disconnection, on the organization and function of sensory and motor cortex. Title: Decoder-compensator architecture for interactive control of high-speed and loaded movements Agency: NSF EFRI Total: $1,600,000 ($400,000 subaward) Duration: 9/1/11 - 8/31/15 Research: This research involves developing a novel model-based Robust Decoder-Compensator (RDC) architecture for interactive control of fast movements in the presence of uncertainty. A unique experimental paradigm will be exploited wherein neural spike and local field potential data from patients with implantable electrodes admitted for epilepsy surgery will be collected. Title: The Role of the Transcallosal Pathway in Neuroplasticity Following Nerve Injury Agency: NIH/NINDS 1R01NS072171-01 (Pelled, PI) Duration: 12/1/2010-11/30/15 Research: The goal of this research is to investigate how modifications in the behavior of inter- hemisphericneuronal pathways affect recovery following peripheral nerve injury and how these pathways can be manipulated in order to promote recovery.
  2. Title: Functional Neuroimaging in Awake, Behaving Animals Agency: NIH/NIBIB 1R21EB012829-01 (Thakor, PI) Duration: 12/01/11-11/30/13 Research: A novel head-mounted microscope for simultaneous optogenetic control of neuronal activity and functional imaging in awake, behaving animals is proposed. Optogenetic control of neuronal activity in freely moving rats involved un behavioral study of texture discrimination will be carried out and images of cerebral blood flow in the barrel cortex fields will be obtained by the head-mounted microscope.
  3. Title: Consequences of Cardiac Arrest: Brain Injury Agency: NHLBI; 1 RO1 HL7156; Principal Investigator: Thakor Project Period: 12/1/08 - 11/30/13 Total Direct Award: 1,678,005 Total Award: 2,735,927 First Year Direct Award: $274,007 First Year Total: $523,386. This is a study into the basic mechanisms of ischemic brain injury. The goal is to use quantitative EEG analysis, evoked potential analysis, neural spike data analysis to determine the different stages of ischemic injury and explore the mechanisms of thalamo cortical neurophysiology, and hypothermic treatment for neuroprotection.
  4. Title: "Collaborative Research: CDI Type I: Optimal and predictive control of neural prostheses using intracortical Brain Machine Interfaces," Agency: National Science Foundation, ECCS-0835554 Co-Principal Investigators: Thakor and M. Kothare (Lehigh Univ) Project Period: 9/1/2008-8/31/2011 Total Direct Award: $146,290 Total Award: $224,999 Description - The goal is to develop a control theoretic architecture and analysis of neural prosthetic devices. Computational and experimental studies of the neural control of sensory and motor prostheses will be carried out in a collaborative project between two institutions.
  5. Title: CRCNS: Dimensionality Reduction in Cortico-Muscular Control of the Hand Co-PI Name: M. H. Schieber (Rochester) and N. V. Thakor (Johns Hopkins) Application ID: 1R01EB010100-01 Project Period: 07/01/2009-06/30/2012 Total Direct: $ 750,000; Total Award: 1,005,750 First Year Direct Award: $250,000 (direct) First Year Total: $344,500 This project will study the decoding of neural population in the M1 motor cortex and derive the basic coding principles of dexterous manipulation using various computational methods to determine if there is synergy in neural coding for various dexterous finger movements and grasps.
  6. Title: Electrocorticographic Studies of Human Cortical Function Agency: NINDS grant no: 3R01NS040596—9A2S1 Co-PI: Nthan E Crone, Nitish V Thakor, and Marc Schieber Total: $873,565 Duration: 9/30/2010-9/29/2012 The goal of this project is to decode Electrocorticographic signals in human subjects and use these signals to control a dexterous prosthetic limb.
Recently completed (Selected)
  1. Title: Formation of Neuromuscular Junction in Microfluidic Chamber Agency: TEDCO (State of Maryland) Principal Investigator: Thakor Project Period: July 1, 2008-June 31, 2010 Total Direct Award: $ 200,000 Total Award: $ 230,000 First Year Direct Award: $ 99,777 First Year Total: $ 114,744 Description - The goal of the project is to develop novel microfabricated chamber in which neuromuscular junction formation can be studied. The project will entail novel fabrication and cell assembly techniques and studying the biology of neuromuscular junction formation.
  2. Title: Surface Myoelectric Control of Hand Prothetics Agency: National Institute of Health, subcontract through Infinite Biomedical Technologies Principal Investigators: Rothman, Neil S. Project Period: 09/15/08- 08/31/11 Total Direct Award: $249,602 Total Award: $373,507 First Year Direct Award: $44,928 First Year Total: $ 73,682 This project will provide trans-radial amputees with intuitive control of current generation prosthetics using surface electromyography (EMG). The technology will also provide a foundation for surface EMG control of fully dexterous prosthetics. Title: Human Embryonic Stem Cell-Derived Oligodendrocytes and Electrophysiological Studies in a Contusion Model of Spinal Cord Injury in the Rat Agency: Technology Development Corporation (TEDCO), State of Maryland (All, PI; Thakor, co-PI) Total: $1,150,000 Duration: 10/1/07-9/3/10 Research on the use of genetically engineered human embryonic and adult stem cells to repair/regenerate spinal cord injury and monitoring spinal cord using somatosensory and motor evoked potentials.
  3. Title: Collaborative Research: Imaging and Modelling of Cortical Microvascular Dynamics Agency: National Institute of Aging; Principal Investigator: G. Cauwenberghs Project Period: 09/01/06 - 08/31/10 Total Direct Award: Current Year Direct Award: $ 106,266 (+64% indirect costs) per year. The aim of this project is to develop a brain vascular imaging system using methods of laser speckle and confocal microscopy. The project will develop novel imaging systems and image analysis algorithms to study microvascular patterns and flows in brain.
  4. Title: Revolutionary Prosthesis 2009 Agency: DARPA, Principal Investigator - Stuart Harshbarger Total: $ 30,000,000 (Phase 1), $ 40,000,000 (Phase II) Duration: 2/1/2006-1/31/2010 This is a major consortium project to design and build a 22 degrees of freedom upper limb prosthesis to be controlled by neural signals including noninvasive and invasive cortical, nerve and muscle signals. The program involves hardware development and decoding neural signals for controlling the prosthesis. Title: Engineering Research Center: Computer Integrated Surgical Systems and Technology, Diagnostic Imaging & Integration Agency: NSF; Principal Investigator: R. Taylor; Project Period: 9/1/99 - 8/31/07; Total: $12,000,000 Center Grant; Total Direct Award: $102,788 ; Current Year Direct Award: $53,400 Current Year Total: 77,978 The aim of this Center is to do research on Computer Integrated surgery, robotics, haptic feedback, vision and imaging. Our project is to develop imaging methods for observing blood flow and haptic feedback in cardiac surgery.
  5. Title: Consequences of Cardiac Arrest: Brain Injury Agency: NHLBI; 1 RO1 HL7156; Principal Investigator: Thakor Project Period: 7/1/03 - 6/30/08; Total Direct Award: $1,500,000 Total Award: $2,400,748 First Year Direct Award: $300,000 First Year Total: $472,403 This is a study into the basic mechanisms of ischemic brain injury. The goal is to use quantitative EEG analysis, neural spike data analysis to determine the different stages of ischemic injury, and explore the mechanisms involving excitotoxicity.
  6. Title: Integrated Electrochemical Microsensor Array Agency: NIMH grant R21 MH 062444; Principal Investigator: N. V. Thakor; Percent Effort: 8% Project Period: 09/17/01 - 07/30/03; Total Direct Award: $ 200,000 Total Awarded: $327,000 Current Year Direct Award: $100,000 Current Year Total: $154,375; A novel multichannel carbon sensor array is proposed to sense and measure neurochemicals from brain tissue. Sensitivity and selectivity to Nitric Oxide will be demonstrated through in vitro and in vivo experimentation.
  7. Title: Multi-function Sensing and Imaging in Brain Tissue Slice Agency: NIMH grant R21MH63159; Principal Investigator: N. V. Thakor; Percent Effort: 20% Project Period: 9/15/02 - 6/30/04; Total Direct Award: $250,000 Total Awarded: $386,799 Current Year Direct Award: $125,000 Current Year Total: $195,168 Design of a microporous glass substrate and optically transparent electrode array is proposed. The aim is to simultaneously sense electrical and optical activity in Hippocampal brain slices.
  8. Title: Quantitative Electrical Measure of Brain Injury Agency: NINDS grant R21NS42690; Principal Investigator: N. V. Thakor; Percent Effort: 16% Project Period: 9/18/02 - 8/31/04; Total Direct Award: $250,000 Total Awarded: $388,312 Current Year Direct Award: $118,750 Current Year Total: $194,156 Quantitative methods, such as time-dependent entropy and wavelet entropy, will be employed to analyze the EEG signals during and after ischemic brain injury. The proposal focuses on developing analytical tools and mathematical algorithms.
  9. Title: Integrated Electronics for Neurotransmitter Sensor Array Agency: NIMH ; 1R21 MH065296; Principal Investigator: Thakor; Effort: 16% Project Period: 7/01/02 - 6/30/04 Total Direct Award: $300,000 Total Award: $477,152; First Year Direct Award: $150,000 First Year Total: $241,755 A very large scale integrated (VLSI) circuit chip is proposed to interface to highly integrated neurotransmitter sensors. The VLSI chip design includes subthreshold design, very sensitive current mode circuitry, implementation of 8 to 16 channel potentiostats and a sigma-delta analog-to-digital converter. The sensor array plus the VLSI chip will be tested on the models of spreading depression and ischemia/preconditioning in brain slices.
  10. Title: Cortical Brain Injury Monitor Agency: NIH/SBIR {Sub-contract from Infinite Biomedical Technologies) Principal Investigator: Thakor; Project Period: 7/1/02 - 6/30/04 Total Direct Award: $285,133 Total Award: $356,416 (Dr. Thakor's allocation only) First Year Direct Award: $120,569 First Year Total: $150,712 Infinite Biomedical Technologies will design and develop a brain injury monitor for use in critical care environment, and implement signal processing. As a part of the Johns Hopkins subcontract, the instrument will be evaluated in patients who experience cardiac arrest and accompanying brain injury.
  11. Title: Spinal Cord Injury Monitor Agency: NIH/SBIR {Sub-contract from Infinite Biomedical Technologies); Principal Investigator: Thakor Project Period: 1/1/03 - 6/30/03; Total Direct Award: $34,119 Total Award: $55,785 First Year Direct Award: $34,119 First Year Total: $55,785 The project's long term focus is on intraoperative monitoring of evoked potential during spinal cord injury. The specific goal of this project is to create an animal model of spinal screw insertion to create graded level of injury, measure the electrophysiologic response with somatosensory evoked potentials, and detect the injury using quantitative signal processing algorithms to analyze the evoked response.
  12. Title: Neonatal Neurological Monitor (N2M) Agency: NIH/SBIR {Sub-contract from Infinite Biomedical Technologies) Principal Investigator: Thakor; Project Period: 5/1/03 - 4/30/05 Total Direct Award: $340,553 Total Award: $482,593 (subcontract) First Year Direct Award: $162,835 First Year Total: $236,815 (subcontract) The project's goal is to develop a novel robust qEEG indicator to provide metrics of the neurological status of the infant after perinatal asphyxia.
  13. Title: Study of Transient Evoked Potentials Agency: NINDS grant NS24282; Principal Investigator: Thakor; Percent Effort: 25% Project Period: 02/01/97 - 01/31/04; Total Direct Award: $1,222,184 Total Awarded: $1,592,317 Current Year Direct Award: $216,943 Current Year Total: $343,462 The aim of this project is to study transient and time-varying evoked potentials in experimental models of neurological injury.

(Book) Quantitative EEG Analysis Methods and Clinical Applications, S. Tong and N. V. Thakor (Eds)., Artech House, Boston, MA, 2009. (Peer-reviewed Scientific Journals
  1. Thakor NV, "Reliable R-wave detection from ambulatory subjects," Biomed Sci Instrum, 14:67-72, 1978.
  2. Thakor NV, Webster JG, "Ground-free ECG recording with two electrodes," IEEE Trans Biomed Eng, 27(12):699-704, 1980.
  3. Tompkins WJ, Thakor NV, "A lecture/laboratory course on microcomputer-based medical instrumentation," IEEE Trans. Educ., 96-101, 1981.
  4. Thakor NV, "A detailed design example - ambulatory ECG monitoring," in Design of Microcomputer- based Medical Instrumentation, W.J. Tompkins and J.G. Webster, (Eds.), Englewood Cliffs, N.J.: Prentice Hall, 1981.
  5. Thakor NV, "Prosthetics," in Design of Microcomputer-based Medical Instrumentation, W.J. Tompkins and J.G. Webster, (Eds.), Englewood Cliffs, N.J.: Prentice Hall, 1981.
  6. Thakor NV, Webster JG, Tompkins WJ, "A battery-powered digital modem for telephone transmission of ECG data," IEEE Trans Biomed Eng, 29(5):355-9, 1982.
  7. Thakor NV, Webster JG, "Design and evaluation of QRS and noise detectors for ambulatory e.c.g. monitors," Med Biol Eng Comput, 20(6):709-14, 1982.
  8. Thakor NV, "A universal program for fully programmable pacemakers," Comput Biol Med, 13(4):271- 9, 1983. http: //www. ncbi.nlm.nih. gov/pubmed/6876910
  9. Thakor NV, Webster JG, Tompkins WJ, "Optimal QRS detector," Med Biol Eng Comput, 21(3):343- 50, 1983.
  10. Thakor NV, Webster JG, Tompkins WJ, "Design, implementation and evaluation of a microcomputer- based portable arrhythmia monitor," Med Biol Eng Comput, 22(2):151-9, 1984.
  11. Shipp GW, Thakor NV, "Multiattribute decision analysis of clinical errors: a case study of computerized arrhythmia detectors," Comput Biomed Res, 17(2):116-28, 1984.
  12. Thakor NV, Webster JG, Tompkins WJ, "Estimation of QRS complex power spectra for design of a QRS filter," IEEE Trans Biomed Eng, 31(11):702-6, 1984.
  13. Thakor NV, "From Holter monitors to automatic defibrillators: developments in ambulatory arrhythmia monitoring," IEEE Trans Biomed Eng, 31(12):770-8, 1984.
  14. Thakor NV, Webster JG, "Electrode studies for the long-term ambulatory ECG," Med Biol Eng Comput, 23(2):116-21, 1985.
  15. Chen S, Thakor NV, Wagner JW, "A microprocessor-based two-channel thromboelastograph," IEEE Trans Biomed Eng, 33(9):887-90, 1986.
  16. Vaz CA, Thakor NV, "Monitoring brain electrical and magnetic activity," IEEE/Eng. in Med. Biol. Magazine, 11-16, 1986.
  17. Thakor NV, Moreau D, "Design and analysis of quantised coefficient digital filters: application to biomedical signal processing with microprocessors," Med Biol Eng Comput, 25(1):18-25, 1987.
  18. Thakor NV, "Adaptive filtering of evoked potentials," IEEE Trans Biomed Eng, 34(1):6-12, 1987.
  19. Thakor NV, McNeela M, "Application of dynamic programming algorithms to kinematics of dexterous hands," J. Robotics Systems, 4:341-3543, 1987.
  20. Chen S, Thakor NV, Mower MM, "Ventricular fibrillation detection by a regression test on the autocorrelation function," Med Biol Eng Comput, 25(3):241-9, 1987.
  21. Lee HS, Cheng QL, Thakor NV, "ECG waveform analysis by significant point extraction. I. Data reduction," Comput Biomed Res, 20(5):410-27, 1987.
  22. Cheng QL, Lee HS, Thakor NV, "ECG waveform analysis by significant point extraction. II. Pattern matching," Comput Biomed Res, 20(5):428-42, 1987.
  23. Becker JC, Thakor NV, "A study of the range of motion of human fingers with application to anthropomorphic designs," IEEE Trans Biomed Eng, 35(2):110-7, 1988.
  24. Kothiyal KP, Shankar B, Fogelson LJ, Thakor NV, "Three-dimensional computer model of electric fields in internal defibrillation," Proc. IEEE, 76(6):720-730, 1988.
  25. Thakor NV, "Cardiac monitoring," in Encyclopedia of Biomedical Instrumentation, J.G. Webster (ed.), Wiley: N.Y., 1988.
  26. Thakor NV, "Computers in electrocardiography," in Encyclopedia of Biomedical Instrumentation, J.G. Webster (ed.), Wiley: N.Y., 1988.
  27. Vaz CA, Thakor NV, "Adaptive Fourier estimation of time-varying evoked potentials," IEEE Trans Biomed Eng, 36(4):448-55, 1989.
  28. Murakawa Y, Gliner BE, Shankar B, Thakor NV, "The effect of an unsuccessful subthreshold shock on the energy requirement for the subsequent defibrillation," Am Heart J, 117(5):1065-9, 1989.
  29. Murakawa Y, Gliner BE, Thakor NV, "Success rate versus defibrillation energy: temporal profile and the most efficient defibrillation threshold," Am Heart J, 118(3):451-8, 1989.
  30. Thakor NV, Eisenman LN, "Three-dimensional computer model of the heart: fibrillation induced by extrastimulation," Comput Biomed Res, 22(6):532-45, 1989.
  31. Thakor NV, Yang M, Amaresan M, Reiter E, Hoehn-Saric R, McCloud D, "A microcomputer-based ambulatory monitor for anxiety disorders," J. Ambulatory Monitoring, 2:277-294, 1989.
  32. Laguna P, Thakor NV, Caminal P, Jane R, Yoon HR, Bayes de Luna A, Marti V, Guindo J, "New algorithm for QT interval analysis in 24-hour Holter ECG: performance and applications," Med Biol Eng Comput, 28(1):67-73, 1990.
  33. Gliner BE, Murakawa Y, Thakor NV, "The defibrillation success rate versus energy relationship: Part I— Curve fitting and the most efficient defibrillation energy," Pacing Clin Electrophysiol, 13(3):326-38, 1990.
  34. Gliner BE, Murakawa Y, Thakor NV, "The defibrillation success rate versus energy relationship: Part II— Estimation with the "bootstrap," Pacing Clin Electrophysiol, 13(4):425-31, 1990.
  35. Laguna P, Thakor NV, Caminal P, Jane R, "Low-pass differentiators for biological signals with known spectra: application to ECG signal processing," IEEE Trans Biomed Eng, 37(4):420-5, 1990.
  36. Thakor NV, Pan K, "Detection of tachycardia and fibrillation: a sequential time domain approach," IEEE Eng. Med. Biol. Magazine (Special Issue on Signal Processing, N.V. Thakor, Guest Ed.), 9:21-24, 1990.
  37. Thakor NV, Zhu YS, Pan KY, "Ventricular tachycardia and fibrillation detection by a sequential hypothesis testing algorithm," IEEE Trans Biomed Eng, 37(9):837-43, 1990.
  38. Bankman IN, Thakor NV, "Noise reduction in biological step signals: application to saccadic EOG," Med Biol Eng Comput, 28(6):544-9, 1990.
  39. Natarajan A, Thakor NV, "Sensors for implantable pacemakers," Med Des Mater, 1(1):58-66, 1991. http: //www
  40. Thakor NV, Natarajan A, "The automatic implantable cardioverter-defibrillator: technology for preventing sudden cardiac death," Med Des Mater, 1(3):16-24, 1991.
  41. Thakor NV, Vaz CA, McPherson RW, Hanley DF, "Adaptive Fourier series modeling of time-varying evoked potentials: study of human somatosensory evoked response to etomidate anesthetic," Electroencephalogr Clin Neurophysiol, 80(2):108-18, 1991.
  42. Thakor NV, Zhu YS, "Applications of adaptive filtering to ECG analysis: noise cancellation and arrhythmia detection," IEEE Trans Biomed Eng, 38(8):785-94, 1991.
  43. Fishler MG, Thakor NV, "A massively parallel computer model of propagation through a two- dimensional cardiac syncytium," Pacing Clin Electrophysiol, 14(11 Pt 2):1694-9, 1991.
  44. Laguna P, Caminal P, Jane R, Thakor NV, Bayes de Luna A, Marti V, "Automatic QT interval analysis in post-myocardial infarction patients," J. Ambulatory Monitoring, 4:93-112, 1991.
  45. Thakor NV, Wu D, Hipsley P, McLeod D, Hoehn-Saric R, "Microcomputer-based design of an ambulatory monitor for generalized anxiety disorders," in Case Studies in Medical Instrument Design, H. T. Nagle and W. J. Tompkins (eds.), pp. 149-162, 1992.
  46. Tucker A, Menkes A, Natarajan A, Ferriz D, Thakor NV, "A microprocessor-based fitness monitor with analog voice feedback for runners," in Case Studies in Medical Instrument Design, H. T. Nagle and W. J. Tompkins (eds.), pp. 163-170, 1992.
  47. Lightfoot JT, Thakor N, Biswijit S, Hanley DF, "Presyncope caused by central hypovolaemia is not preceded by evoked potential alterations," Clin Physiol, 12(3):267-75, 1992.
  48. Laguna P, Jane R, Meste O, Poon PW, Caminal P, Rix H, Thakor NV, "Adaptive filter for event-related bioelectric signals using an impulse correlated reference input: comparison with signal averaging techniques," IEEE Trans Biomed Eng, 39(10):1032-44, 1992.
  49. Province RA, Fishler MG, Thakor NV, "Effects of defibrillation shock energy and timing on 3-D computer model of heart," Ann Biomed Eng, 21(1):19-31, 1993.
  50. Nathan SS, Lesser RP, Gordon B, Thakor NV, "Electrical stimulation of the human cerebral cortex. Theoretical approach," Adv Neurol, 63:61-85, 1993.
  51. Thakor NV, Guo XR, Vaz CA, Laguna P, Jane R, Caminal P, Rix H, Hanley DF, "Orthonormal (Fourier and Walsh) models of time-varying evoked potentials in neurological injury," IEEE Trans Biomed Eng, 40(3):213-21, 1993.
  52. Nathan SS, Sinha SR, Gordon B, Lesser RP, Thakor NV, "Determination of current density distributions generated by electrical stimulation of the human cerebral cortex," Electroencephalogr Clin Neurophysiol, 86(3):183-92, 1993.
  53. Nathan SS, Lesser RP, Gordon B, Thakor NV, "Simulations of electrical stimulation of the human cerebral cortex," in Electrical and Magnetic Stimulation of Brain and Spinal Cord, A. Beric and M. Dogah (eds.), Raven Press: N.Y., pp. 113-137, 1993.
  54. Thakor NV, Sun Y, Rix H, Caminal P, "MULTIWAVE: a wavelet-based ECG data compression algorithm," IEICE Trans. Information, Systems (Japan), E76-D:1462-1469, 1993.
  55. Thakor NV, Guo XR, Sun YC, Hanley DF, "Multiresolution wavelet analysis of evoked potentials," IEEE Trans Biomed Eng, 40(11):1085-94, 1993.
  56. Vaz CA, Kong X, Thakor NV, "An adaptive estimation of periodic signals using a Fourier linear combiner," IEEE Trans. Sig. Proc., 42(1):1-10, 1994.
  57. Baykal A, Ranjan R, Thakor NV, "Model-based analysis of the ECG during early stages of ventricular fibrillation," J Electrocardiol, 27 Suppl:84-90, 1994.
  58. Thakor NV, Natarajan A, Tomaselli GF, "Multiway sequential hypothesis testing for tachyarrhythmia discrimination," IEEE Trans Biomed Eng, 41(5):480-7, 1994.
  59. Thakor NV, "Adaptive filters for analysis of intra-cardiac signals," Med Biol Eng Comput, 32(4 Suppl):S19-24, 1994.
  60. Meste O, Rix H, Caminal P, Thakor NV, "Ventricular late potentials characterization in time-frequency domain by means of a wavelet transform," IEEE Trans Biomed Eng, 41(7):625-34, 1994.
  61. Yi-Sheng Z, Bin Z, Thakor NV, "Variable convergence adaptive filter and its application to cardiac action potentials," Med Biol Eng Comput, 32(6):673-8, 1994.
  62. Fishler MG, Thakor NV, "A computer model study of the ventricular fibrillation vulnerable window: sensitivity to regional conduction depressions," Ann Biomed Eng, 22(6):610-21, 1994.
  63. Fishler MG, Sobie EA, Tung L, Thakor NV, "Cardiac responses to premature monophasic and biphasic field stimuli. Results from cell and tissue modeling studies," J Electrocardiol, 28 Suppl:174-9, 1995.
  64. Thakor NV, Kong X, Hanley DF, "Nonlinear changes in brain's response in the event of injury as detected by adaptive coherence estimation of evoked potentials," IEEE Trans Biomed Eng, 42(1):42-51, 1995. http: //www. ncbi.nlm.nih. gov/pubmed/7851929
  65. Poon P, Koehler RC, Thakor NV, "Rapid measurement of somatosensory evoked potential response to cerebral artery occlusion," Med Biol Eng Comput, 33(3 Spec No):396-402, 1995.
  66. Thakor NV, Sherman D, "Wavelet (time-scale) analysis in biomedical signal processing," in The Biomedical Engineering Handbook, J. Bronzino (Ed.), CRC Press, 886-906, 1995.
  67. Ferrari M, Williams MA, Wilson DA, Thakor NV, Traystman RJ, Hanley DF, "Cat brain cytochrome-c oxidase redox changes induced by hypoxia after blood-fluorocarbon exchange transfusion," Am J Physiol, 269(2 Pt 2):H417-24, 1995.
  68. Gramatikov B, Yi-Chun S, Rix H, Caminal P, Thakor NV, "Multiresolution wavelet analysis of the body surface ECG before and after angioplasty," Ann Biomed Eng, 23(5):553-61, 1995.
  69. Ranjan R, Thakor NV, "Electrical stimulation of cardiac myocytes," Ann Biomed Eng, 23(6):812-21, 1995. http: //www. ncbi.nlm.nih. gov/pubmed/8572431
  70. Laguna P, Jane R, Olmos S, Thakor NV, Rix H, Caminal P, "Adaptive estimation of QRS complex wave features of ECG signal by the Hermite model," Med Biol Eng Comput, 34(1):58-68, 1996.
  71. Riviere CN, Thakor NV, "Effects of age and disability on tracking tasks with a computer mouse: accuracy and linearity," J Rehabil Res Dev, 33(1):6-15, 1996.
  72. Kong X, Thakor NV, "Adaptive estimation of latency changes in evoked potentials," IEEE Trans Biomed Eng, 43(2):189-97, 1996.
  73. Fishler MG, Sobie EA, Thakor NV, Tung L, "Mechanisms of cardiac cell excitation with premature monophasic and biphasic field stimuli: a model study," Biophys J, 70(3):1347-62, 1996.
  74. Riviere CN, Thakor NV, "Modeling and canceling tremor in human-machine interfaces," IEEE Eng. Med. Biol., 15(3):29-36, 1996.
  75. Brauna JC, Hanley DF, Thakor NV, "Detection of neurological injury using time-frequency analysis of the somatosensory evoked potential," Electroencephalogr Clin Neurophysiol, 100(4):310-8, 1996. http: //www
  76. Ferrero JM Jr, Saiz J, Ferrero JM, Thakor NV, "Simulation of action potentials from metabolically impaired cardiac myocytes. Role of ATP-sensitive K+ current," Circ Res, 79(2):208-21, 1996.
  77. Thakor NV, Kong X, "Analyses of transient and time-varying evoked potentials of detection of brain injury," in Advances in Processing and Pattern Analysis of Biological Signals, I. Gath and G. Inbar (eds), Plenum Press, pp. 145-166, 1996.
  78. Thakor NV, Baykal A, Casaleggio A, "Fundamental analyses of ventricular fibrillation signals by parametric, nonparametric, and dynamical methods," in Advances in Processing and Pattern Analysis of Biological Signals, I. Gath and G. Inbar (eds), pp. 273-296, Plenum Press, 1996.
  79. Casaleggio A, Corana A, Ranjan R, Thakor NV, "Dimensional analysis of the electrical activity in fibrillating isolated hearts," Int. J. Bifurc. Chaos, 6(8): 1547-1561, 1996.
  80. Stingele R, Wagner B, Kameneva MV, Williams MA, Wilson DA, Thakor NV, Traystman RJ, Hanley DF, "Reduction of cytochrome-c oxidase copper precedes failing cerebral O2 utilization in fluorocarbon-perfused cats," Am J Physiol, 271(2 Pt 2):H579-87, 1996.
  81. Goel V, Brambrink AM, Baykal A, Koehler RC, Hanley DF, Thakor NV, "Dominant frequency analysis of EEG reveals brain's response during injury and recovery," IEEE Trans Biomed Eng, 43(11):1083-92, 1996. http: //www. ncbi.nlm.nih. gov/pubmed/9214826
  82. Fishler MG, Sobie EA, Tung L, Thakor NV, "Modeling the interaction between propagating cardiac waves and monophasic and biphasic field stimuli: the importance of the induced spatial excitatory response," J Cardiovasc Electrophysiol, 7(12):1183-96, 1996.
  83. Thakor NV, Ranjan R, Rajasekhar S, Mower MM, "Effect of varying pacing waveform shapes on propagation and hemodynamics in the rabbit heart," Am J Cardiol, 79(6A):36-43, 1997.
  84. Baykal A, Ranjan R, Thakor NV, "Estimation of the ventricular fibrillation duration by autoregressive modeling," IEEE Trans Biomed Eng, 44(5):349-56, 1997.
  85. Riviere CN, Reich SG, Thakor NV, "Adaptive Fourier modeling for quantification of tremor," J Neurosci Methods, 74(1):77-87, 1997.
  86. Sherman DL, Tsai YC, Rossell LA, Mirski MA, Thakor NV, "Spectral analysis of a thalamus-to-cortex seizure pathway," IEEE Trans Biomed Eng, 44(8):657-64, 1997.
  87. Ranjan R, Chiamvimonvat N, Thakor NV, Tomaselli GF, Marban E, "Mechanism of anode break stimulation in the heart," Biophys J, 74(4):1850-63, 1998.
  88. Thakor NV, "Biopotentials and electrophysiology," in The Measurements, Instrumentation, and Sensors Handbook, J.G. Webster (Ed.), Boca Raton, FL: CRC Press, 1998.
  89. Riviere CN, Rader RS, Thakor NV, "Adaptive canceling of physiological tremor for improved precision in microsurgery," IEEE Trans Biomed Eng, 45(7):839-46, 1998.
  90. Muthuswamy J, Thakor NV, "Spectral analysis methods for neurological signals," J Neurosci Methods, 83(1): 1-14, 1998.
  91. Thakor NV, Ferrero JM Jr, Saiz J, Gramatikov BI, Ferrero JM Sr, "Electrophysiologic models of heart cells and cell networks," IEEE Eng Med Biol Mag, 17(5):73-83, 1998.
  92. Park JK, Tran PH, Chao JK, Ghodadra R, Rangarajan R, Thakor NV, "In vivo nitric oxide sensor using non-conducting polymer-modified carbon fiber," Biosens Bioelectron, 13(11):1187-95, 1998.
  93. Muthuswamy J, Sherman DL, Thakor NV, "Higher-order spectral analysis of burst patterns in EEG," IEEE Trans Biomed Eng, 46(1):92-9, 1999.
  94. Saiz J, Ferrero JM Jr, Monserrat M, Ferrero JM, Thakor NV, "Influence of electrical coupling on early afterdepolarizations in ventricular myocytes," IEEE Trans Biomed Eng, 46(2):138-47, 1999.
  95. Muthuswamy J, Tran P, Rangarajan R, Lenz FA, Hanley DF, Thakor NV, "Somatosensory stimulus entrains spindle oscillations in the thalamic VPL nucleus in barbiturate anesthetized rats," Neurosci Lett, 262(3):191-4, 1999.
  96. Zhang XS, Zhu YS, Thakor NV, Wang ZM, Wang ZZ, "Modeling the relationship between concurrent epicardial action potentials and bipolar electrograms," IEEE Trans Biomed Eng, 46(4):365-76, 1999. http: //www
  97. Zhang XS, Zhu YS, Thakor NV, Wang ZZ, "Detecting ventricular tachycardia and fibrillation by complexity measure," IEEE Trans Biomed Eng, 46(5):548-55, 1999.
  98. Kong X, Brambrink A, Hanley DF, Thakor NV, "Quantification of injury-related EEG signal changes using distance measures," IEEE Trans Biomed Eng, 46(7):899-901, 1999.
  99. Sherman DL, Brambrink AM, Ichord RN, Dasika VK, Koehler RC, Traystman RJ, Hanley DF, Thakor NV, "Quantitative EEG during early recovery from hypoxic-ischemic injury in immature piglets: burst occurrence and duration," Clin Electroencephalogr, 30(4):175-83, 1999.
  100. Muthuswamy J, Sherman DL, Thakor NV, "Message from the Brain," in Medical Diagnostic Techniques and Procedures, M. Singh et al. (eds)., pp. 82-94, 1999.
  101. Thakor NV, Tsai YC, Meyer MA, George PM, Bandyopadhyay A, "Medical Microsystems," in Medical Diagnostic Techniques and Procedures, M. Singh et al. (eds)., pp. 256-265, 1999.
  102. Shenai M, Gramatikov B, Thakor NV, "Computer Models of Depolarization Alterations Induced By Myocardial Ischemia: The Effect of Superimposed Ischemic Inhomogeneities on Propagation in Space-, Time-, and Time-Frequency Domains," J. Biol. Systems (Special Issue), 1-22, 1999.
  103. Geocadin RG, Muthuswamy J, Sherman DL, Thakor NV, Hanley DF, "Early electrophysiological and histologic changes after global cerebral ischemia in rats," Mov Disord, 15 Suppl 1:14-21, 2000.
  104. Johnson LJ, Hanley DF, Thakor NV, "Optical light scatter imaging of cellular and sub-cellular morphology changes in stressed rat hippocampal slices," J Neurosci Methods, 98(1):21-31, 2000.
  105. Gramatikov B, Brinker J, Yi-chun S, Thakor NV, "Wavelet analysis and time-frequency distributions of the body surface ECG before and after angioplasty," Comput Methods Programs Biomed, 62(2):87-98, 2000.
  106. Thakral A, Stein LH, Shenai M, Gramatikov BI, Thakor NV, "Effects of anodal vs. cathodal pacing on the mechanical performance of the isolated rabbit heart," J Appl Physiol, 89(3):1159-64, 2000.
  107. Geocadin RG, Ghodadra R, Kimura T, Lei H, Sherman DL, Hanley DF, Thakor NV, "A novel quantitative EEG injury measure of global cerebral ischemia," Clin Neurophysiol, 111(10):1779-87, 2000.
  108. Zhang JW, Liu JR, Zheng CX, Tao WZ, Thakor NV, Xie A, "Noninvasive early detection of focal cerebral ischemia," IEEE Eng Med Biol Mag, 19(6):74-81, 2000.
  109. Monserrat M, Saiz J, Ferrero JM Jr, Ferrero JM, Thakor NV, "Ectopic activity in ventricular cells induced by early afterdepolarizations developed in Purkinje cells," Ann Biomed Eng, 28(11):1343-51, 2000. http: //www .ncbi.nlm.nih. gov/pubmed/11212952
  110. George P, Muthuswamy J, Curie J, Thakor NV, Paranjape P, "Fabrication of screen-printed carbon electrode arrays for sensing neuronal messengers, " Biomedical Microdevices, 3(4): 307-317, 2001.
  111. Lee YJ, Zhu YS, Xu YH, Shen MF, Tong SB, Thakor NV, "The nonlinear dynamical analysis of the EEG in schizophrenia with temporal and spatial embedding dimension," J Med Eng Technol, 25(2) :79- 83, 2001.
  112. Hongxuan Z, Yisheng Z, Yuhong X, Thakor NV, "Pathological analysis of myocardial cell under ventricular tachycardia and fibrillation based on symbolic dynamics," J Med Eng Technol, 25(3):112-7, 2001. http: //www .ncbi.nlm.nih. gov/pubmed/11530825
  113. Lee YJ, Zhu YS, Xu YH, Shen MF, Zhang HX, Thakor NV, "Detection of non-linearity in the EEG of schizophrenic patients," Clin Neurophysiol, 112(7):1288-94, 2001.
  114. Boustany NN, Kuo SC, Thakor NV, "Optical scatter imaging: subcellular morphometry in situ with Fourier filtering," Opt Lett, 26(14):1063-5, 2001.
  115. Tong S, Bezerianos A, Paul J, Zhu Y, Thakor N, "Removal of ECG interference from the EEG recordings in small animals using independent component analysis," J Neurosci Methods, 108(1):11-7, 2001.
  116. Wang Y, Zhu YS, Thakor NV, Xu YH, "A short-time multifractal approach for arrhythmia detection based on fuzzy neural network," IEEE Trans Biomed Eng, 48(9):989-95, 2001.
  117. Luft AR, Kaelin-Lang A, Hauser TK, Cohen LG, Thakor NV, Hanley DF, "Transcranial magnetic stimulation in the rat," Exp Brain Res, 140(1):112-21, 2001.
  118. Paul JS, Luft AR, Hanley DF, Thakor NV, "Coherence-weighted Wiener filtering of somatosensory evoked potentials," IEEE Trans Biomed Eng, 48(12):1484-8, 2001.
  119. Tong S, Bezerianos A, Paul J, Zhu Y, Thakor NV, "Nonextensive entropy measure of EEG following brain injury from cardiac arrest," Physica A, 305(3-4):619-628, 2002.
  120. Muthuswamy J, Kimura T, Ding MC, Geocadin R, Hanley DF, Thakor NV, "Vulnerability of the thalamic somatosensory pathway after prolonged global hypoxic-ischemic injury," Neuroscience, 115(3):917-29, 2002.
  121. McIntyre CC, Thakor NV, "Uncovering the mechanisms of deep brain stimulation for Parkinson's disease through functional imaging, neural recording, and neural modeling," Crit Rev Biomed Eng, 30(4-6):249-81, 2002.
  122. Sauer CM, Tomlin DH, Mozaffari Naeini H, Gerovichev O, Thakor NV, "Real-time measurement of blood vessel occlusion during microsurgery," Comput Aided Surg, 7(6):364-70, 2002.
  123. Luft AR, Kaelin-Lang A, Hauser TK, Buitrago MM, Thakor NV, Hanley DF, Cohen LG, "Modulation of rodent cortical motor excitability by somatosensory input," Exp Brain Res, 142(4):562-9, 2002.
  124. Sherman DL, Atit MK, Geocadin RG, Venkatesha SV, Hanley DF, Natarajan AL, Thakor NV, "Diagnostic instrumentation for neurological injury," IEEE Instrum. Measurement Mag., 5:28-35, 2002.
  125. Bandyopadhyay A, Johnson L, Chung W, Thakor NV, "Protection by rapid chemical preconditioning of stressed hippocampal slice: a study of cellular swelling using optical scatter imaging," Brain Res, 945(1):79-87, 2002.
  126. Boustany NN, Drezek R, Thakor NV, "Calcium-induced alterations in mitochondrial morphology quantified in situ with optical scatter imaging," Biophys J, 83(3):1691-700, 2002.
  127. Geocadin RG, Sherman DL, Christian Hansen H, Kimura T, Niedermeyer E, Thakor NV, Hanley DF, "Neurological recovery by EEG bursting after resuscitation from cardiac arrest in rats," Resuscitation, 55(2): 193-200, 2002.
  128. Johnson LJ, Chung W, Hanley DF, Thakor NV, "Optical scatter imaging detects mitochondrial swelling in living tissue slices," Neuroimage, 17(3):1649-57, 2002.
  129. Boardman A, Schlindwein FS, Thakor NV, Kimura T, Geocadin RG, "Detection of asphyxia using heart rate variability," Med Biol Eng Comput, 40(6):618-24, 2002.
  130. Luft AR, Buitrago MM, Paul JS, Hagan J, Ding MC, Thakor N, Hanley DF, "Early restitution of electrocorticogram predicts subsequent behavioral recovery from cardiac arrest," J Clin Neurophysiol, 19(6):540-6, 2002.
  131. Bezerianos A, Tong S, Thakor N, "Time-dependent entropy estimation of EEG rhythm changes following brain ischemia," Ann Biomed Eng, 31(2):221-32, 2003.
  132. Boustany N. and Thakor N. V., "In-Vitro Monitoring of Cells and Thin Biological Specimens with Elastic Light Scattering Techniques," in Biomedical Photonics Handbook, Editor: Tuan Vo-Dinh, Ph.D., CRC press, Boca Raton, FL, p 16.1-16.23, 2003.
  133. Mirski MA, Tsai YC, Rossell LA, Thakor NV, Sherman DL, "Anterior thalamic mediation of experimental seizures: selective EEG spectral coherence," Epilepsia, 44(3):355-65, 2003.
  134. Al-Nashash HA, Paul JS, Ziai WC, Hanley DF, Thakor NV, "Wavelet entropy for subband segmentation of EEG during injury and recovery," Ann Biomed Eng, 31(6):653-8, 2003.
  135. Passeraub PA, Almeida AC, Thakor NV, "Design, microfabrication and characterization of a microfluidic chamber for the perfusion of brain tissue slices," Biomedical Microdevices, 5:147-155, 2003.
  136. Tsai YC, Fishman PS, Thakor NV, Oyler GA, "Parkin facilitates the elimination of expanded polyglutamine proteins and leads to preservation of proteasome function," J Biol Chem, 278(24):22044- 55, 2003.
  137. Tong S, Bezerianos A, Malhotra A, Zhu Y, Thakor N, "Parameterized entropy analysis of EEG following hypoxic-ischemic brain injury," Phys Lett A, 314(5-6):354-361, 2003.
  138. Paul JC, Patel CB, Zhang N, Ziai WC, Mirski MA, Sherman DL, "Sequential Detection of PTZ-Induced Seizures Using Wavelet-based Residual Entropy," IEEE Trans. Biomed. Eng. (Special Issue on Seizure Predictions and Devices), 49:640-648, 2003.
  139. Ray S, Jouny CC, Crone NE, Boatman D, Thakor NV, Franaszczuk PJ, "Human ECoG analysis during speech perception using matching pursuit: a comparison between stochastic and dyadic dictionaries," IEEE Trans Biomed Eng, 50(12):1371-3, 2003.
  140. Moraru L, Cimponeriu L, Tong S, Thakor N, Bezerianos A, "Characterization of heart rate variability changes following asphyxia in rats," Methods Inf Med, 43(1):118-21, 2004.
  141. Thakor NV, Tong S, "Advances in quantitative electroencephalogram analysis methods," Annu Rev Biomed Eng, 6:453-95, 2004.
  142. McIntyre CC, Mori S, Sherman DL, Thakor NV, Vitek JL, "Electric field and stimulating influence generated by deep brain stimulation of the subthalamic nucleus," Clin Neurophysiol, 115(3):589-95, 2004.
  143. McIntyre CC, Grill WM, Sherman DL, Thakor NV, "Cellular effects of deep brain stimulation: model- based analysis of activation and inhibition," J Neurophysiol, 91(4):1457-69, 2004.
  144. Lau WW, Ramey NA, Corsco JJ, Thakor NV, Hager GD, "Stereo based endoscopic tracking of cardiac surface deformation," Medical Image Computing and Computer Assisted Intervention, MCCAI-2004, Lecture Notes in Computer Science, Springer-Verlag, pp. 494-501, 2004.
  145. Al-Nashash H, Al-Assaf Y, Paul J, Thakor N, "EEG signal modeling using adaptive Markov process amplitude," IEEE Trans Biomed Eng, 51(5):744-51, 2004.
  146. Sherman DL, Patel CB, Zhang N, Rossell LA, Tsai YC, Thakor NV, Mirski MA, "Sinusoidal modeling of ictal activity along a thalamus-to-cortex seizure pathway I: new coherence approaches," Ann Biomed Eng, 32(9): 1252-64, 2004.
  147. Buitrago MM, Luft AR, Thakor NV, Blue ME, Hanley DF, "Effects of somatosensory electrical stimulation on neuronal injury after global hypoxia-ischemia," Exp Brain Res, 158(3):336-44, 2004.
  148. Thakor NV, Iyer V, Shenai M, "From Cellular Electrophysiology to Electrocardiography," Modeling and Imaging of Bioelectric Activity: Principles and Applications, He, B. (Ed), Kluwer Academic/Plenum Pub: N. Y., pp. 1-38, 2004.
  149. Boustany NN, Tsai YC, Pfister B, Joiner WM, Oyler GA, Thakor NV, "BCL-xL-dependent light scattering by apoptotic cells," Biophys J, 87(6):4163-71, 2004.
  150. Lau W, Tong S, Thakor NV, "Spatiotemporal characteristics of low-frequency functional activation measured by laser speckle imaging," IEEE Trans Neural Syst Rehabil Eng, 13(2):179-85, 2005.
  151. Moraru L, Tong S, Malhotra A, Geocadin R, Thakor N, Bezerianos A, "Investigation of the effects of ischemic preconditioning on the HRV response to transient global ischemia using linear and nonlinear methods," Med Eng Phys, 27(6):465-73, 2005.
  152. Sauer C, Stanacevic M, Cauwenberghs G, and Thakor NV, "Power Harvesting and Telemetry in CMOS for Implanted Devices," IEEE Trans. Circuits and Systems I: Regular Papers, Special Issue on "Biomedical Circuits and Systems: A New Wave of Technology, 52(12):2605-2613, 2005.
  153. Ye D, Mozaffari-Naeini H, Busart C, Thakor NV, "MEMSurgery: an integrated test-bed for vascular surgery," Int J Med Robot, 1(3):21-30, 2005.
  154. Murari K, Stanacevic M, Cauwenberghs G, Thakor NV, "Integrated potentiostat for neurotransmitter sensing. A high sensitivity, wide range VLSI design and chip," IEEE Eng Med Biol Mag, 24(6):23-9, 2005.
  155. Al-Nashash HA, Thakor NV, "Monitoring of global cerebral ischemia using wavelet entropy rate of change," IEEE Trans Biomed Eng, 52(12):2119-22, 2005.
  156. Geocadin RG, Malhotra AD, Tong S, Seth A, Moriwaki G, Hanley DF, Thakor NV, "Effect of acute hypoxic preconditioning on qEEG and functional recovery after cardiac arrest in rats," Brain Res, 1064(1-2): 146-54, 2005.
  157. Koenig MA, Kaplan PW, Thakor NV, "Clinical neurophysiologic monitoring and brain injury from cardiac arrest," Neurol Clin, 24(1):89-106, 2006.
  158. Koskinen M, Seppanen T, Tong S, Mustola S, Thakor NV, "Monotonicity of approximate entropy during transition from awareness to unresponsiveness due to propofol anesthetic induction," IEEE Trans Biomed Eng, 53(4):669-75, 2006.
  159. Cai Y, Qiu Y, Wei L, Zhang W, Hu S, Smith PR, Crabtree VP, Tong S, Thakor NV, Zhu Y, "Complex character analysis of heart rate variability following brain asphyxia," Med Eng Phys, 28(4):297-303, 2006.
  160. Shin HC, Tong S, Yamashita S, Jia X, Geocadin RG, Thakor NV, "Quantitative EEG and effect of hypothermia on brain recovery after cardiac arrest," IEEE Trans Biomed Eng, 53(6):1016-23, 2006.
  161. Thakor NV, Shin HC, Tong S, Geocadin RG, "Quantitative EEG assessment," IEEE Eng Med Biol Mag, 25(4):20-5, 2006.
  162. Zhang H, Venkatesha S, Minahan R, Sherman D, Oweis Y, Natarajan A, Thakor NV, "Intraoperative Neurological monitoring. Continuous evoked potential signal extraction and analysis," IEEE Eng Med Biol Mag, 25(4):39-45, 2006.
  163. Vogelstein RJ, Etienne-Cummings R, Thakor NV, Cohen AH, "Phase-dependent effects of spinal cord stimulation on locomotor activity," IEEE Trans Neural Syst Rehabil Eng, 14(3):257-65, 2006.
  164. Vogelstein J., Tenore F., Etienne-Cummings R., Lewis M. A., Thakor N. V. and Cohen A., "Control of Locomotion After Injury or Amputation," Biological Cybernetics, Vol. 95, No. 6, pp. 555 - 566, December 2006.
  165. Thakor NV, Tong S, "Therapeutic technologies in neuroengineering," IEEE Eng Med Biol Mag, 25(5):30-1, 2006.
  166. Jia X, Koenig MA, Shin HC, Zhen G, Yamashita S, Thakor NV, Geocadin RG, "Quantitative EEG and neurological recovery with therapeutic hypothermia after asphyxial cardiac arrest in rats," Brain Res, 1111(1): 166-75, 2006.
  167. Hong B, Acharya S, Ku Y, Gao S, Thakor N V, "Measurement of dynamic coupling of independent EEG components from cognitive tasks," Int J. Bioelctro. Mag, Vol. 8, No. 1, pp. VII/1 - VII/7, 2006. http: //www.rgi. tut. fi/ij bem/volume 8/number 1/htm/hong.htm
  168. Koskinen, M.; Seppanen, T.; Tong S. Mustola, S.; Thakor, N.V., "Monotonicity of approximate entropy during transition from awareness to unresponsiveness due to propofol anesthetic induction," IEEE Trans. Biomed. Eng., Vol. 53, Issue: 4, pp. 669-675, 2006. 10.1109/TBME.2006.870230
  169. Tong S, Jiang D, Wang Z, Zhu Y, Geocadin RG, Thakor NV, "Long range correlations in the heart rate variability following the injury of cardiac arrest," Physica A, 380:250-258, 2007.
  170. Murari K, Li N, Rege A, Jia X, All A, Thakor NV, "Contrast-enhanced imaging of cerebral vasculature with laser speckle," Appl Opt, 46(22):5340-6, 2007.
  171. Schreckinger M, Geocadin RG, Savonenko A, Yamashita S, Melnikova T, Thakor NV, Hanley DF, "Long-lasting cognitive injury in rats with apparent full gross neurological recovery after short-term cardiac arrest," Resuscitation, 75(1):105-13, 2007.
  172. Tong S, Li Z, Zhu Y, Thakor NV, "Describing the nonstationarity level of neurological signals based on quantifications of time-frequency representation," IEEE Trans Biomed Eng, 54(10):1780-5, 2007.
  173. Chatterjee A, Aggarwal V, Ramos A, Acharya S, Thakor NV, "A brain-computer interface with vibrotactile biofeedback for haptic information," J Neuroeng Rehabil, 4:40, 2007.
  174. Aggarwal V, Acharya S Tenore F, Etienne-Cummings R, Schieber MH, Thakor NV, "Asynchronous Decoding of Dexterous Finger Movements using M1 Neurons," IEEE Trans Neural Syst Rehab. Eng, 16(1):3-14, 2008.
  175. Acharya S, Tenore F, Aggarwal V, Etienne-Cummings R, Schieber MH, Thakor NV, "Decoding individuated finger movements using volume-constrained neuronal ensembles in the M1 hand area," IEEE Trans Neural Syst Rehabil Eng, 16(1):15-23, 2008.
  176. Jia X, Koenig MA, Shin HC, Zhen G, Pardo CA, Hanley DF, Thakor NV, Geocadin RG, "Improving neurological outcomes post-cardiac arrest in a rat model: Immediate hypothermia and quantitative EEG monitoring," Resuscitation, 76(3):431-42, 2008.
  177. Jia X, Koenig MA, Nickl R, Zhen G, Thakor NV, Geocadin RG, "Early electrophysiologic markers predict functional outcome associated with temperature manipulation after cardiac arrest in rats," Crit Care Med, 36(6):1909-16, 2008.
  178. Jia X, Koenig MA, Venkatraman A, Thakor NV, Geocadin RG, "Post-cardiac arrest temperature manipulation alters early EEG bursting in rats," Resuscitation, 78(3):367-73, 2008.
  179. Shin HC, Jia X, Nickl R, Geocadin RG, Thakor NV, "A subband-based information measure of EEG during brain injury and recovery after cardiac arrest," IEEE Trans Biomed Eng, 55(8):1985-90, 2008.
  180. All AH, Aggarwal V, Thakor NV, "Evaluation of Human Performance in Manual Blood Vessel Compression," Int. J. Cardiovascular Med.Sci., Vol. III, No 2, pp 113-117, 2008.
  181. Mollazadeh M, Murari K, Cauwenberghs G., and Thakor NV, "Micropower CMOS integrated low- noise amplification, filtering, and digitization of multimodal neuropotentials," IEEE Trans. Biomed. Circuits Systems, Vol. 3, No. 1, pp. 1-10, 2009.
  182. All AH, Gerovichev O, Sauer C, Naware M, Thakor NV. "Haptic and Visual Feedback Achieves Minimum Occlusion Force in Vascular Surgery" Int. J. Cardiovascular Med.Sci., Vol. 6, No 1, pp 17¬24, 2009.
  183. Murari K, Thakor N V, Cauwenberghs G, "Which photodiode to use: a comparison of CMOS- compatible structures," IEEE Sensors J., vol. 9, no. 7, pp. 752-760, 2009.
  184. Tenore F., Ramos A., Acharya S., Etienne-Cummings R. and Thakor N. V., "Decoding of individuated finger movements using surface electromyography," IEEE Trans. Biomed. Eng., Vol. 56(5), pp. 1427¬1434, 2009.
  185. Li N, Jia X, Murari K, Parlapalli R, Rege A, Thakor NV, "High spatiotemporal resolution imaging of the neurovascular response to electrical stimulation of rat peripheral trigeminal nerve as revealed by in vivo temporal laser speckle contrast," J Neurosci Methods, Vol. 176, pp. 230-236, 2009.
  186. Kang X, Geocadin R, Thakor NV, Maybhate A, " Multiscale entropy analysis of EEG for assessment of post-cardiac-arrest neurological recovery under hypothermia in rats," IEEE Trans. Biomed. Eng., Vol. 56(4), pp. 1023-1031, 2009.
  187. Koenig M. A., Jia X, Kang X, Velasquez A, Thakor NV, and Geocadin RG, "Intraventricular Orexin-A improves arousal and early EEG entropy in rats after cardiac arrest," Brain Res, Vol. 1255, pp.153-161, 2009 .
  188. Shin H-C, Aggarwal V., Acharya S., Scheiber MH, and Thakor N. V., "Neural decoding of finger movements using Skellam based maximum likelihood decoding," IEEE Trans. Biomed. Eng., Vol. 57(3), pp. 754-60, 2009.
  189. All A H, Walczak P, Agrawal G, Gorelik2,4, Lee MC, Thakor NV, Bulte JWM, and Kerr DA , "Effect of MOG sensitization on somatosensory evoked potential in Lewis rats," J. Neurol. Sci., Vol. 284, Issues 1-2, pp, 81-89, 2009. doi: 10.1016/j.jns.2009.04.025.
  190. Yang IH, Siddique R, Hosmane S, Thakor NV, and Hoke A, "Compartmentalized microfluidic culture platform to study mechanism," Expt. Neurol., Vol. 218(1), pp. 124-128, 2009.
  191. Al Nashash H, Fatoo NA, Mirza NM, Ahmed R, Agrawal G, Thakor NV and All AH, "Spinal cord injury detection and monitoring using spectral coherence", IEEE Trans Biomed Eng., Vol. 56(8):1971- 9. Epub 2009 Apr 7.
  192. All AH, Walczak P, Agrawal G, Lee C, Thakor NV, Bulte JWM and Kerr DA, "Effect of MOG sensitization on somatosensory evoked potential in Lewis rats," J. Neurological Sci., Vol. 284(1-2):8 1¬9. Epub 2009 May 6.
  193. Agrawal G, Thakor NV, and All AH, "Evoked Potential versus behavior to detect minor insult to spinal cord in rat model," J. Clin. Neurosci., Vol. 16(8), pp.1052-1055. 2009 May 5. http: //www
  194. Agarwal G, Kerr C, Thakor N V and All A, "Characterization of graded MASCIS contusion spinal cord injury using somatosensory evoked potential" Spine, 2010 Mar 27. http: //www
  195. Singhal G, Aggarwal V, Acharya S, Aguayo J, He J, Thakor NV, " Ensemble fractional sensitivity: a quantitative approach to neuron selection for decoding motor tasks," Comput. Intell. Neurosci., Vol. 2010 (2010), Article ID 648202, 9 pages, doi:10.1155/2010/648202.
  196. Hosmane S, Yang IH, Ruffin A, Thakor N, Venkatesan A., "Circular compartmentalized microfluidic platform: Study of axon-glia interactions," Lab Chip, Vol. 10(6), pp. 741-747, 2010.
  197. Letzen BS, Liu C, Thakor NV, Gearhart JD, All AH and Kerr CL, "MicroRNA expression profiling of oligodendrocyte differentiation from human embryonic stem cells", PLoS ONE, 2010 May 5;5(5):e10480.
  198. Agrawal G, Sherman DL, Maybhate A, Gorelik M, Kerr DA, Thakor NV, and All AH, "Slope analysis of somatosensory evoked potentials in spinal cord injury: Detecting contusion injury or focal demyelination (EAE)," J. Clinical Neurosci., 2010 Sep;17(9):1159-64. Epub 2010 Jun 9.
  199. Kerr C, Letzen BS, Hill C, Agrawal G, Thakor NV, Sterneckert J, Gearhart J and All AH, "Efficient differentiation of human embryonic stem cells into oligodendrocyte progenitors for application in a rat contusion model of spinal cord injury," Int. J. Neurosci., Vol. 120(4), pp. 305-313, 2010.
  200. Berger TW, Chen Z, Cichocki A, Oweiss KG, Quiroga RQ and Thakor NV, " Signal Processing for Neural Spike Trains," Editorial, Computational Intelligence and Neurosci., Vol. 2010 (2010), Article ID 698751, 2 pages, doi:10.1155/2010/698751.
  201. Xiong W, Koenig M, Madhok J, Jia X, Puttgen HA, Thakor NV, and Geocadin RG, "Evolution of somatosensory evoked potentials after cardiac arrest induced hypoxic-ischemic injury," Resuscitation, Vol. 81(7):893-897, 2010. Epub 2010 Apr 24.
  202. Choi Y, Koenig MA, Jia X, and Thakor NV, "Quantifying time-varying multiunit neural activity using entropy based measures," IEEE Tran. Biomed. Eng, Vol. 57, pp. 2771 - 2777, 2010. doi: 10.1109/TBME.2010.2049266
  203. Madhok J, Maybhate A, Xiong W, Koenig MA, Geocadin, RG, Jia X, Thakor NV, "Quantitative assessment of somatosensory evoked potentials after cardiac arrest in rats: prognostication of functional outcomes" Critical Care Med., Vol. 38(8), pp. 1709-1717, 2010.
  204. Acharya S., Fifer MS, Benz HL, Crone NE, and Thakor NV, "Electrocorticographic amplitude predicts finger positions during slow grasping motions of the hand," J Neural Eng., Vol. 7(4), 2010. doi: 10.1088/1741-2560/7/4/046002,
  205. All AH, Agrawal G, Walczak P, Maybhate A, Bulte JW, Kerr DA, "Evoked potential and behavioral outcomes for experimental autoimmune encephalomyelitis (EAE) in Lewis rats, " Neurol Sci., Vol. 7(4):046002, 2010. Epub 2010 May 20.
  206. Agrawal G, Sherman D, Maybhate A, Gorelik M, Kerr DA, Thakor NV, All AH, "Slope analysis of somatosensory evoked potentials in spinal cord injury for detecting contusion injury and focal demyelination, " J Clinc Neurosci., Vol. 17(9):1159-1164, 2010. Epub 2010 Jun 9.
  207. Wu D, Anastassios B, Xiong W, Madhok J, Jia X, Thakor NV, "Study of the Origin of Short- and Long- latency SSEP during Recovery from Brain Ischemia in a Rat Model, " Neurosci Lett, Vol. 13, 2010 Sep 13.
  208. Murari K., Etienne Cummings R., Thakor N. V., Cauwenberghs G, "A CMOS In-Pixel CTIA High Sensitivity Fluorescence Imager", IEEE Trans. Biomed. Circ. and Sys., Vol. 5 (5), pp. 449 - 458, 2011. 10.1109/TBCAS.2011.2114660.
  209. Hur E.-M., Yang I. H., Kim D.-H., Byun J., Xu W.-L., Saijilafu S., Nicovich P., Cheong R., Levchenko A., Thakor N. V., Zhou F.-Q., "Inhibition of nonmuscle myosin II promotes axon growth over inhibitory molecules by regulating growth cone dynamics and microtubule structures " PNAS, doi:10.1073/pnas. 1011258108, pp. 1-6, 2011.
  210. Greenwald E., Mollazadeh M., Hu C., Tang W., Culurciello E., and Thakor N. V. "A VLSI Neural Monitoring System with Ultra-Wideband Telemetry for Awake Behaving Subjects," IEEE Trans. Biomed. Circuits. Systems, Vol. 5 (2), pp. 112-119, 2011. 10.1109/TBCAS.2011.2141670.
  211. Markus A., Grigoryan S., Sloutskin A., Yee M. B., Zhu H., Yang I. H., Thakor N. V., Sarid R., Kinchington P. R., and Goldstein R. S., "Varicella zoster virus infection of neurons derived from human embryonic stem cells: direct demonstration of axonal infection, transport of VZV and productive neuronal infection," J. Virol., Vo. 85(13), pp. 6220-6233, 2011.
  212. Li N., Downey J., Bar-Shir A., Gilad A. A., Walczak P., Kim H., Joel S. E., Pekar J. J., Thakor N. V. and Pelled G., "Optogenetically-guided cortical plasticity following nerve injury," Proc. Natl. Acad. Sci., Vol. 108(21):8838-43, May 24, 2011.
  213. Ma Y., Hu Y., Valentin N., Geocadin R. G., Thakor N. V., Jia X., "Time jitter of somatosensory evoked potentials in recovery from hypoxic-ischemic brain injury, J. Neurosci. Methods, accepted, 2011.
  214. Benz H. L., Zhang H., Bezerianos A., Acharya S., Crone N. E., Zheng X., and Thakor N. V., Connectivity analysis as a novel approach to decoding for prosthesis control," IEEE Trans. Neural Systems Rehab. Eng., .accepted, 2011.
  215. Maybhate A., Hu C., Bazley F.A., Yu Q., Thakor N. V., Kerr C.L., and All A. H. "Potential long-term benefits of acute hypothermia after spinal cord injury: Assessments with somatosensory-evoked potentials", Crit Care Med., 2011, PMID 22001581,
  216. Zhang H., Benz H. L., Thakor N. V., and Bezerianos A., "Connectivity mapping of human brain by phase-based evolution map approach," Int. J. Bifurc. Chaos, accepted, 2011.
  217. Mollazadeh M., Aggarwal V., Davidson A. G., Law A. J., Thakor N. V. and Schieber M. H., "Spatiotemporal variation of multi-modal neural activity in the primary motor cortex during dexterous reach-to-grasp movements," J. Neurosci., Vol. 31(43), pp. 15531-15543, 2011.
  218. Hosmane S., Fournier A., Wright R., Rajbhandari L., Siddique R., Yang I. H., Ramesh K. T., Venkatesan A. and Thakor N. V., "Valve-based microfluidic compression platform: single axon injury and regrowth," Lab Chip, 2011, Advance Article DOI: 10.1039/C1LC20549H
  219. Maybhate A., Hu C., Bazley F. A., Yu Q. Thakor N. V., Kerr C. L., and All A. H., "Potential long-term benefits of acute hypothermia after spinal cord injury: Assessments with somatosensory-evoked potentials," Crit. Care Med., doi: 10.1097/CCM.0b013e318232d97e, Oct, 2011.
  220. Sherman D. L, Zhang N., Garg S., Thakor N. V., Mirksi M. A., White M. A., Hinich M. J.,"Detection of nonlinear interactions of EEG Alpha waves in the brain by a new coherence measure and its application to epilepsy," Int. J. Neural Systems, Vol. 21, No. 2, pp. 115-126, 2011. DOI: 10.1142/S0129065711002754
  1. Rege A., Thakor N. V., Rhie K., and Pathak A. P., "In vivo laser speckle contrast imaging reveals microvascular remodeling and hemodynamic changes during wound healing angiogenesis," under review.
  2. Rege A., Murari K., Seifert A., Thakor N. V., "Multi exposure laser speckle contrast imaging of the angiogenic environment," J. Biomed. Optics, under review.
  3. Kim H-M., Kim Y-H., Shin H-C., Aggarwal V., and Thakor N. V., "Neuron selection by relative importance for neural decoding of dexterous finger movements," under review.
  4. Parmar M., Smith R. J., Kilevskaya N. and Thakor N. V., "Design and validation of a myoelectric joystick for trans-radial amputees," under preparation.
  5. Wu D., Xiong W., Jia X., Geocadin R., and Thakor N. V.," Effects of hypothermia on short- and long-latency somatosensory neuronal responses following hypoxic-Ischemic Brain Injury," under review.
  6. Liu R., Newman G. I., Ying S. H., Thakor N. V., "Decision speedup in motor imagery brain-computer Interfaces using sequential hypothesis testing," under review.
  7. Kortelainen J., Jia X., Seppanen T., Thakor N. V., "Spectrum and quantitative parameters of electroencephalogram in rats during isoflurane anesthesia," under preparation.
  8. Aggarwal V., Mollazadeh M., Davidson A. G., Schieber M. H., and Thakor N. V., "Decoding hand and finger kinematics using neuronal ensemble and LFP activity from motor and premotor areas during a reach and grasp task," under preparation.
  9. Rege A., Senarathna J., Li N., and Thakor N. V., "Anisotropic processing of laser speckle images improves spatiotemporal resolution," under review.
  1. Cheung D., Christman C. and Thakor N. V., "Automated Method and Apparatus for Determining Characteristics of Nerve Fibers," with D. Cheung and C. Christman," U.S. Patent No. 5,231,580; Issued 7/27/93.
  2. Thakor N. V."Magnetocentrifugation," U. S. Patent No. 5,565,105, 1996.
  3. Natarajan A. and Thakor N.V., "Implantable Myocardial Ischemia Detection, Indication and Action
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    1. Post-doctoral and Pre-doctoral Trainees Selected Past Pre-Doctoral and Doctoral Trainees
      • Kang X., Madhok J., Miao P; Murari K., Acharya A., Agrawal G., Zhang D , Aggarwal M., Singhal G., Vogelstein J., Chatterjee A., Cho Y-J., Koskinen M., Lau W, Wallace J, Sauer C., Naware M., Brooke J, Gerovichev O., Agrawal M., Sarje A., Mulliken G., George P., Tsai Y-C, Johnson L., Chung W., Ghodardra R, Bandyopadhyay A., Atit M. K., M-C Ding; Ramos A, Thakral A., Stein L., Shenai M. H., Tong S., Godhadra, R., Riviere, C. N., Ranjan, R., Rajasekhar, S., Fishler M. G., Stingele, R., Goel, V., Braun J., Yi-chun S., Poon P., Meste O., Natarajan, A., Vaz C. A., Bin Z., Xin-rong G., Nathan S. S., Province R.A., Biswajit A., Pan K., Gliner B.E., Yang M., Amaresan M., Reiter E., Shankar B., Becker J.C., Cheng Q., Lee H.S., Shoupu C., McNeela M., Didier M.,
    2. Selected Past Post Doctoral Fellows and Research Associates
      • Choi Y., Shin H-C, Ye D., Hong B., Tong S, Boustany N., Buitrago M. M., Sherman D., McIntyre C. C., Paul J. C., Passeraub P. A., Almeida A. C., Luft A. R., Gramatikov B., Kimura T., Muthuswamy J., Saiz J., Ferrero J. M. (Jr), Geocadin R. G., Park, J.-K., Lei H, Hatib F, Baykal A., Kong, X., Laguna P., Yi-Sheng Z., Bankman I.N., Murakawa Y., Kothiyal K.P.
    3. Present Pre-Doctoral and Doctoral Trainees:
      • Rege A., Mollazadeh M., Nan L., Aggarwal V., Smith R., Hosmane S., Siddique R., Greenwald E., Newman G., Benz H., Fifer M., Senarathana J., Wu D., Ma Y., Trachtenberg M., Ying M., Bazely F., Rupp, K.
    4. Present Post-Doctoral Fellows:
      • Yang I., Maybhate A., Kaliki R., Xiong W.
    5. Present Research Faculty/Associates:
      • All A.; Jia X, Sherrman D.
    6. Present Clinical Research Associates/Collaborators:
      • Geocadin R., Ying S., Crone N., Ewen J.